AIM Hyperamylasemia after congenital heart disease surgery in children and infants has been reported for many years. Only a few study aimed to explore the trend of blood amylase of these children. Our research is to explore the influencing factors of delayed peak blood amylase elevation in children after congenital heart disease post-operation.
METHODS This is a retrospective study. 180 children were included with 3 times higher blood amylase after congenital heart disease from January 1 to December 31 of 2019 in Fuwai hospital undergoing repair of congenital heart disease. They were divided to 2 groups according to whether blood amylase reach to peak in 48 hours after surgery. To identify the risk factor of delayed peak blood amylase, a logistic regression was used.
RESULTS Overall, there are no significance statistical difference in basic demographic characteristics, CPB(Cardiopulmonary bypass), ACC(aortic cross clamp) and other biochemical indicators. The patients with delayed peak blood have longer CPB time, ICU time and were more likely right heart disease. The logistic regression analysis suggests right heart disease was an independent risk factor of delayed peak blood amylase(P = 0.002; Odds Ratio OR 5.205, 95% Confidence Interval CI 1.801–15.047).
CONCLUSION The right heart disease was an independent risk factor of delayed peak blood amylase in children after repair of congenital heart disease.
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