Qi LIU, Hai-jing ZHAO, Long CHENG, Yu-qi LIU. Research progress of mTOR in coronary heart disease[J]. Chinese Heart Journal, 2020, 32(6): 631-635, 641. DOI: 10.12125/j.chj.202007008
    Citation: Qi LIU, Hai-jing ZHAO, Long CHENG, Yu-qi LIU. Research progress of mTOR in coronary heart disease[J]. Chinese Heart Journal, 2020, 32(6): 631-635, 641. DOI: 10.12125/j.chj.202007008

    Research progress of mTOR in coronary heart disease

    • The mammalian target of rapamycin (mTOR) is atypical serine/threonine protein kinase,which interacts with specific proteins to form mTORC1 and mTORC2 complexes.mTOR signaling pathway plays a key role in the regulation of protein synthesis, autophagy, survival, and stress in cells.More studies show that mTOR signaling pathway plays an important role in the occurrence and development of coronary heart disease. This article mainly discusses the mechanism of mTOR in coronary heart disease.
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