Impact of PCI on the quality of life in coronary heart disease patients of CTO with previous CABG

  AIM  To observe the impact of percutaneous coronary intervention (PCI) on the quality of life of chronic total occlusion (CTO) patients with previous CABG.

  METHODS  123 CTO patients with successful PCI from the Department of Cardiology, Xijing Hospital from August 2010 to August 2018 were enrolled continuously. All these patients were divided into two groups: non-CABG group and CABG group. The clinical data of patients were collected. Postoperative major adverse cardiovascular events (MACE) were followed up. The changes of quality of life between two groups were compared by Seattle angina pectoris scale (SAQ) and SF-12 scale.

  RESULTS  The LVEF values and LDL-C of patients in the CABG group were obviously below the non-CABG group (P<0.01). In the imaging results, the proportion of LM combined with two or three coronary lesions in CABG group was obviously higher than that of non-CABG group, and the proportion of non-LM single- or two-coronary lesions in CABG group was significantly lower than that of non-CABG group (P<0.05, P<0.01). During the average follow-up time after PCI (47±3 months), the all-cause mortality rate of patients in CABG group was higher than that of non-CABG group and the rate of recurrent non-fatal myocardial infarction and clinically driven revascularization in non-CABG group is higher than that of CABG group, but there was no significance between two groups. The scores for physical activity limitation of SAQ in CABG group were higher than that of non-CABG group (68±7) vs. (59±2), the scores for angina pectoris steady state of SAQ in CABG group were higher than that of non-CABG group (70±9) vs. (46±6) and the scores for angina pectoris attack frequency of SAQ in CABG group were obviously higher than that of non-CABG group (88±8) vs. (80±6), the difference was statistically significant (P<0.05). However, there was no significant difference in treatment satisfaction and disease cognition. The physiological scores of SF-12 scale in CABG group were significantly higher than that of non-CABG group (46±5) vs. (39±4), P<0.05). But the psychological scores of the two groups were not statistically significant.

  CONCLUSION  Successful PCI improves the angina symptoms and quality of life of CTO patients with previous CABG.