AIM To demonstrate gender-related difference in risk factors, clinical manifestation, and treatment of aortic dissection in young patients.
METHODS Young patients with aortic dissection were enrolled in this study and clinical data were analyzed and compared between different genders.
RESULTS A total of 518 patients were recruited in this study. Among them, there were 431 males (83%) and 87 females (17%). The proportion of the following clinical data was significantly higher in male than that in female: awareness of medical history of hypertension at first admission (62% vs. 38%, P<0.01), smoking habit (50% vs. 13%, P<0.01), alcohol abuse (15% vs. 7%, P<0.05), huge abdominal circumference with >110 cm in male or >100 cm in female (23% vs. 9%, P<0.01), type A dissection (54% vs. 40%, P<0.05), cardiac tamponade (14% vs. 6%, P<0.05) and respiratory complication (18% vs. 9%, P<0.05). The difference in BMI≥32, hyperlipaemia, hyperuricemia, involvement of coronary artery, superior mesenteric artery ischemia, lower limb ischemia, conservative treatment, circulatory complication, neurologic complication, renal complication and mortality between male and female was not significant.
CONCLUSION Gender-related difference in risk factor, clinical manifestation, and treatment does exist in young patients with aortic dissection.
DownLoad: