AIM To observe the changes of quality of life after percutaneous coronary intervention (PCI) in patients with unprotected left main (ULMCA) coronary heart disease.
METHODS Clinical data, including age, gender, past history, personal history, operation history, vital signs, body mass index, blood lipids, blood sugar, renal function and left ventricular ejection fraction, were collected in 74 patients with ULMCA lesions who underwent successful PCI in the Department of Cardiology of Xijing Hospital from September 2017 to December 2019, and postoperative adverse events, including all-cause death, non-fatal myocardial infarction and clinically driven revascularization, were followed up. The changes of quality of life before and after PCI were compared by measuring SF-12 scale and Seattle angina pectoris scale.
RESULTS Among the 74 cases with unprotected left main coronary heart disease, there were a large proportion of males (82%), 41 cases with hypertension (55%), 22 cases with diabetes (30%), 25 cases with smoking history (34%) and the median body mass index (BMI) was 24 (23, 27) kg/m2. The degree of stenosis of the left main artery was (68 ±16)% and the Gensini score was (140 ± 43). The left main lesion was mainly at the opening (60%), with a large proportion of three-vessel coronary artery disease (95%), a median total stent length of 88 (47, 113) mm, a median operation duration of 178 (108, 270) minutes and a median contrast agent dose of 300 (195, 400) ml. During the follow-up after PCI (mean 5.06 months), all-cause death occurred in 3 cases (4%) and revascularization of target vessels in 4 cases (6%). Univariate analysis showed that when the age of the patient increased by one year, the incidence of postoperative MACE increased by 1.15 times. The scores of SF-12 scale and SAQ in patients with ULMCA disease after PCI were significantly higher than those before operation (P<0.05, P <0. 01).
CONCLUSION PCI treatment improves the quality of life of patients with coronary heart disease with ULMCA disease.
DownLoad: