Coronary heart disease and its risk factors in COVID-19 patients with mild symptoms: clinical characteristics summary

  AIM   To analyze coronary heart disease and risk factors of initial COVID-19 patients admitted in Wu Han Huo Shen-Shan hospital. To evaluate cardiovascular diagnosis types in patients with COVID-19 patients and outcomes.

  METHODS   Medical history and laboratory data of a total of 65 initial COVID-19 patients admitted in Wu Han Huo Shen-Shan hospital were retrospectively analyzed. All patients had mild symptoms whose type of diagnosis were common (34 patients) and severe (31 patients). Current and past medical histories were collected by inquiry and electronic medical record systems. Laboratory data included CK, CK-MB, D-dimers, plasma albumin and total rotein.

  RESULTS   of the 65 total patients, the median time from early symptoms to hospitalization was 14 days. Demographics included age 54±12 years with 39 males. The present investigation defined “comprehensive definition of coronary heart disease and risk factors” as to evaluate cardiovascular risk in patients, which was a composite of coronary heart disease or diabetes mellitus or hypertension or smoking. There were 27 patients who met the definition with a ratio of 42%. 15 patients were severe type and 12 patients were common. In hypertensive patients, utilization of calcium antagonists was 11 patients (61%), ACEI/ARB was 8 patients (44%). 7 patients had diabetes mellitus. Among the 16 patients who tested CK and CK-MB after admission, CK abnormal rate was 25% and normal in CK-MB. Among the 27 patients who tested D-dimers, 11 patients were abnormal, the rate was 41%. There were 17 patients tested BNP with no abnormal. Among the 27 patients who tested plasma albumin and total protein, 24 patients’ plasma albumin were abnormal, the rate was 86%, 21 patients’ plasma total protein were abnormal, the rate was 75%. All 65 patients recovered and were discharged.

  CONCLUSION   There were a high level of “comprehensive definition of coronary heart disease and risk factors” in the 65 first group COVID-19 patients admitted in Wu Han Huo Shen-Shan hospital, and all patients recovered. The results of this investigation suggest that COVID-19 patients with common or severe diagnose type complicated with coronary heart disease and its risk factors overall have a good prognosis once hospitalized.