Relaxin and vascular endothelial cells

Relaxin (RLX) was first discovered as a pregnancy-related hormone. In recent years, the vasoprotective effect of relaxin has attracted wide attention. Endothelial cells, as a basic component of the inner wall of vasculars, have a significant effect on vasculars. Studies have shown that relaxin can cause endothelium-dependent vasodilation, reduce vascular resistance and increase circulating blood flow. In this article, we summarize the effects of relaxin on vascular endothelial cells and its signal transduction pathway, and clarify the relationship between relaxin and vascular endothelial cells, aiming to provide new therapeutic options for clinical treatment of cardiovascular diseases.