Prognostic factors of patients with Stanford type A aortic dissection receiving CRRT due to AKI post cardiac surgery

  AIM  To analyze prognostic factors of patients with Stanford type A aortic dissection receiving continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI) post cardiac surgery.

  METHODS  Patients with AKI receiving CRRT after cardiac surgery for type A aortic dissection in Xijing Hospital from April 2015 to March 2018 were screened. Patients were divided into two groups: survival arm(n = 32), death arm (n = 34), and the clinical data before, during and after operation were recorded..

  RESULTS  Sixty-six patients were enrolled, with age of 49 (±9) years, 91% of them were males, and the preoperative serum creatinine was 144(±77) μmol/L. Among them, 34 patients died(52%).Multivariate logistic regression analysis showed that intraoperative erythrocyte transfusion (HR = 3.169, 95% CI 1.180-8.513; P <0.05) and postoperative multiple organ failure (HR = 3.575, 95% CI 1.196-10.687; P <0.05) were independent risk factors for death in patients with Stanford type A aortic dissection receiving CRRT due to AKI post cardiac surgery.

  CONCLUSION  More red blood cells injected during the operation and multiple organ failure after the operation may suggest higher risk of death in AKI patients requiring CRRT after surgery for type A aortic dissection.