Research progress in potassium channel and arrhythmia induced by obesity
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Graphical Abstract
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Abstract
Obesity predisposes to arrhythmia and treatment is limited. Existing evidence suggests that obesity-induced arrhythmia is associated with abnormal cardiac potassium channels. The study of cardiac potassium channel expression and electrophysiological mechanism in obese patients should improve understanding of obesity-induced arrhythmia, potentially discover new pathological mechanisms, and identify potentially new therapeutic targets. Given the worldwide epidemic of obesity, this information could be highly beneficial for obese patients. This article, therefore, reviews research progress of cardiac potassium channels and arrhythmia induced by obesity.
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