Interventional thrombolysis combined with implantation of inferior vena cava filter in treating deep venous thrombosis of lower extremities

AIM:To evaluate the therapeutic effect of interventional thrombolysis combined with implantation of inferior vena cava filter for deep venous thrombosis of lower extremities (LEDVT). METHODS: Clinical data were analyzed in 84 patients with LEDVT from October 2008 to October 2011. Fifty one cases in the observation group were treated with interventional thrombolysis combined with implantation of inferior vena cava filter and conventional anticoagulation treatment, whereas 33 cases in the control group were treated with conventional anticoagulation and thrombolysis. The efficacy in the two groups was evaluated. RESULTS: The efficacy rates in the observation group upon hospital discharge and at 3-month follow-up were significantly higher than those in control group (98% vs. 58%; 98% vs. 79%; both P<0.01). Bleeding complications and incidence of pulmonary embolusin the observation group were significantly reduced (4% vs. 27%, P<0.05; 0% vs. 12%, P<0.01). Incidence of deep vein thrombosis syndrome in the observation group was lower than in control group (2% vs. 15%, P<0.05). CONCLUSION: Interventional thrombolysis combined with proper implantation of inferior vena cava filter for LEDVT has a superior therapeutic effect than conventional thrombolysis treatment and can effectively prevent or reduce the occurrence of pulmonary embolism.