Relationship between prevalence of morning blood pressure surge and components of metabolic syndrome

AIM:To investigate the prevalence of morning blood pressure surge (MBPS) and the components of metabolic syndrome (MetS). METHODS: A total of 322 patients with essential hypertension (EH) were enrolled and divided into two groups: EH and MetS group (EH+MS, n=126) and EH and non-MetS group (EH+nMS, n=196) and ambulatory blood pressure were recorded. RESULTS: Twenty four-hour SBP, dSBP, nSBPP, 24 h PP, dPP, nPP and MBPS were significantly higher in EH+MS group than in EH+nMS group (P<0.05 or P<0.01). The incidence of morning blood pressure in EH+MS group was higher than that in EH+NMS group (P<0.01). Pearson relation analysis and multiple regression analysis showed that morning blood pressure levels were positively correlated with age, fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), systolic blood pressure (SBP), PP, body mass index (BMI) and waist circumference (WC). After adjusting other risk factors, TC, age, FPG, SBP and WC remained as predisposing risk factors for MBPS levels. CONCLUSION: MetS correlates closely with morning blood pressure surge. TC, age, FPG, SBP and WC are independently associated with the prevalence of morning blood pressure surge.