Re-recognization of “stenosis” and “plaque” in ischemic heart disease

Ischemic heart pathogenesis is a multi-factorial and complex disease, which involves vessels, blood, myocardium, and psychological aspects. Numerous previous reviews have focused on anatomic injury, anoxia, or cardiovascular events, but recent clinical data challenges these traditional factors. Therefore, this review takes a new look at “stenosis” and stenosis elimination treatment, preferably finding potential better solutions to the contradiction between factorial treatment and clinical outcome.