Progress in caveolae and caveolae-mediated endocytosis in cardiovascular disease

Caveolae are mainly composed of caveolins and cavins. Caveolae are involved in many cellular functions including mechanosensing, signaling, endocytosis, lipid storage and trafficking, cell metabolism and membrane homeostasis. Caveolae-mediated endocytosis plays an important role in many pathophysiological processes and is associated with a variety of diseases. In this review, the composition of caveolae, caveolae-mediated endocytosis and caveolae-related cardiovascular diseases will be introduced.