AIM To analyze the relationship between monocyte to HDL-C ratio (MHR) and non-culprit vessel lesion (NCL) progression with percutaneous coronary intervention (PCI) in patients.
METHODS Clinical data of 132 patients who had percutaneous coronary intervention from January 2016 to December 2018 and had reexamination of coronary angiography before December 2019 in Jiangyin People's Hospital.They were divided into NCL progression group (62 cases) and NCL progression-free group (73 cases).Basic information and the correlation between MHR and NCL progression were analyzed.
RESULTS Level of ApoB,fasting blood glucose and MHR in NCL progression group were significantly higher than those in NCL progression-free group (all P<0.05). The degree of stenosis in NCL progression-free group was significantly higher than that in NCL progression-free group, and PCI was also significantly higher than NCL progression-free group (all P<0.01). Receiver operating characteristic curve showed that the boundary point of MHR to predict NCL progression was 0.375 with the sensitivity and specificity at 60% and 56% respectively,the area under curve (AUC) were 0.604 (95% confidence interval:0.510～0.699). Logistic regression showed that MHR (odds ratio=2.217, 95% confidence interval:1.092～4.501, P<0.05) and fasting blood glucose (odds ratio=1.900, 95% confidence interval:1.020～3.540, P<0.05) were risk factor.
CONCLUSION There is a correlation between MHR and NCL progression after PCI in patients.
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