AIM To evaluate the value of left ventricular myocardium T2* in quantitative evaluation of different coronary artery blood supply areas in elderly patients with type 2 diabetes mellitus (T2DM) with no complications.
METHODS Prospectively collected for this study were 17 elderly T2DM cases without complications (age ≥ 60 years, 7 males and 10 females), 37 non-elderly T2DM cases without complications (age <60 years, 18 males and 19 females) and healthy elderly 12 volunteers who served as controls (age ≥ 60 years, 5 males and 7 females). T2*Mapping sequence was used to scan their left ventricular short axis and their duration of diabetes and body mass index were recorded. The differences of T2* values of left ventricular myocardium in the left anterior descending artery (LAD), left circumflex artery (LCX) and right coronary artery (RCA) were compared between the above three groups and the correlation of T2* values of the left ventricular coronary artery supply segment and the duration of diabetes and body mass index was analyzed.
RESULTS The T2* value of LCX supply ventricular myocardium in elderly T2DM group was lower than that in healthy control group and the difference was statistically significant (P<0.05). There was no significant difference in T2* values between LAD and RCA supply ventricular myocardium in the above three groups (all P>0.05). There was no correlation between T2* value of left ventricular myocardium and the duration of diabetes and body mass index in elderly T2DM patients without complications.
CONCLUSION The T2* value of the ventricular myocardium in the left circumflex donor region in elderly T2DM group has decreased, suggesting that the myocardium may be hypoxic.
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