AIM To compare the differences in parameters of 12 lead routine electrocardiogram (ECG) and echocardiography between patients with hypertrophic cardiomyopathy (HCM) and hypertension induced left ventricular hypertrophy (H-LVH). To evaluate the ECG in detecting patients with HCM and H-LVH.
METHODS Healthy individuals and patients with H-LVH or HCM were enrolled (n=49 in each group). ECG parameters were analyzed, including P wave duration, QTC duration, QRS duration, abnormal Q wave, the amplitude of R wave and S wave. E/A ratio, left ventricular ejective fraction (LVEF), maximum left ventricular wall thickness (MLVWT), left atrial diameter, systole of the left and right left ventricle, diastolic phase of the left and right left ventricle, systolic phase of the left ventricle anterior and posterior diameter, diastolic phase of the left ventricle anterior and posterior diameter, systole of the long axis of the left ventricle, diastolic phase of the long axis of the left ventricle were measured by conventional echocardiography. The above parameters were compared between groups.
RESULTS Compared with the H-LVH group, patients with HCM presented with increased LVEF and MLVWT (P < 0.05). However, Per stroke output, systole of the left and right left ventricle, diastolic phase of the left and right left ventricle, systolic phase of the left ventricle anterior and posterior diameter, diastolic phase of the left ventricle anterior and posterior diameter, systole of the long axis of the left ventricle, diastolic phase of the long axis of left ventricle of H-LVH group were significantly higher in patients with H-LVH than patients with HCM (P < 0.05).
CONCLUSION Compared with patients with H-LVH, patients with HCM had a higher QRS voltages in leads II, III, aVF, V1 and V2 and prolonged QTC duration(P < 0.01). The abnormal Q wave proportion and QRS main wave direction were consistent with T waves in lead III and aVR was higher in the HCM group.
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