Long-xiang DENG, Fang-jun MOU, Yi LIU, Qi LIU, Wang-wei YANG, Lin-ying XIA, Qi SUN, Ling TAO, Ming YUAN. Impact of restenosis pattern on clinical outcomes after simple paclitaxel-coated balloon angioplasty for in-stent restenosis[J]. Chinese Heart Journal, 2019, 31(3): 270-273, 277. DOI: 10.1212/j.chj.201811017
    Citation: Long-xiang DENG, Fang-jun MOU, Yi LIU, Qi LIU, Wang-wei YANG, Lin-ying XIA, Qi SUN, Ling TAO, Ming YUAN. Impact of restenosis pattern on clinical outcomes after simple paclitaxel-coated balloon angioplasty for in-stent restenosis[J]. Chinese Heart Journal, 2019, 31(3): 270-273, 277. DOI: 10.1212/j.chj.201811017

    Impact of restenosis pattern on clinical outcomes after simple paclitaxel-coated balloon angioplasty for in-stent restenosis

    •   AIM  To discuss the relationship between the pattern of in-stent restenosis (ISR) and clinical prognosis in patients treated with a Paclitaxel-coated Balloon (PCB).
        METHODS  246 patients with one target lesions were screened from 283 patients who underwent coronary angiography. These patients were diagnosed with ISR and treated with PCB. The 246 patients were divided into a focal lesion group (n = 101) and a non-focal lesion group (n = 145). The primary end point was target lesion revasculation (TLR) at 12 months. Secondary end points were 12-month major adverse cadiac events (MACE) (e.g., cardiac death, myocardial infarction, and TLR), and target vessel revascularization, all-cause death, and stent thrombosis. RESULTS There was no significant difference in clinical baseline data between the two groups. The rate of compliance balloon in the non-focal group was higher than that in the focal group (P < 0.01) and the length was longer (P = 0.01). the diameter of the cutting was larger in the focal group than that in the non-focal group (P < 0.05). The diameter of PCB in the focal group was larger (P < 0.01), and the length was shorter (P < 0.01). The event-free survival analysis of these 246 patients showed that the survival rate of TLR-free events in the focal group (P < 0.05) and the survival rate without MACE events (P < 0.05) were superior to those in the non-focal group.
        CONCLUSION  AfterAfter PCB angioplasty for ISR, the morphologic pattern of ISR is also an important predictor of outcomes. The use of PCB for in-stent restenosis is safe and effective.
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