血栓抽吸导管在冠脉介入治疗中对血栓病变TIMI血流的影响

王智; 唐强; 陈学智; 史振涛

血栓抽吸导管在冠脉介入治疗中对血栓病变TIMI血流的影响

Effect of thrombus aspiration catheter on TIMI flow during percutaneous coronary intervention for patients with thrombotic burden lesion

摘要

摘要: 目的: 探讨血栓抽吸导管在经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)中对于血栓病变TIMI血流的影响。方法：对我院1年来急性冠脉综合征(ACS）冠状动脉造影（CAG）显示靶病变相关血管(target- related artery,TRA) 血栓负荷的患者48（男35，女13)例，年龄（58±8）岁，随机分成试验组（血栓抽吸＋PCI，n=25）与对照组（直接PCI，n=23）。收集所有病例的临床和CAG资料，对比两组患者PCI术中相关血管心肌梗死溶栓试验(thrombolysis in myocardial infarction，TIMI)血流情况。结果：试验组患者PCI术中无复流及慢血流发生率明显低于对照组（0% vs. 17%，P<0.05），两组患者PCI术后TIMI Ⅲ级血流无显著差异。结论：对于冠脉有血栓负荷病变进行血栓抽吸可以明显改善ACS患者IRA远端的前向血流，降低无复流现象的发生。

Abstract: AIM：To study the effect of thrombus aspiration catheter on TIMI flow during percutaneous coronary intervention (PCI) for patients with thrombotic burden lesion. METHODS: Forty-eight patients (35 men and 13 women, mean age 58±8 years) with acute coronary syndrome (ACS) were divided into two groups: intracoronary thrombus aspiration+PCI group (n=25) and primary PCI group (n=23). Effects of thrombus aspiration catheter on TIMI flow during procedure were observed. RESULTS: The rates of slow-flow and no-reflow in intracoronary thrombus aspiration+PCI group was lower than that in primary PCI group (0% vs. 17%, P<0.05) and no significant difference was observed in TIMI III flow grade between the two groups after procedure. CONCLUSION: Intracoronary thrombus aspiration+PCI is a more effective reperfusion method before PCI for ACS patients with lower rates of no-reflow.

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