Abstract: AIM：To explore the relationship between the levels of blood pressure and factors such as age, sex, body mass index (BMI), waist size, pulse pressure, total plasma cholesterol, plasma triglycerides, fasting blood glucose, incidence of coronary artery diseases, cerebral hemorrhage, and cerebral infarction in subjects with normal blood pressure. METHODS: Data such as age, sex, BMI, waist size, pulse pressure, total plasma cholesterol, plasma triglycerides, fasting blood glucose, incidence of coronary artery disease, cerebral hemorrhage and cerebral infarction were observed in a group of 1533 consecutive subjects with normal blood pressure. The relationship between these risk factors and blood pressure levels was studied. RESULTS: A significant difference was observed in age, sex, BMI, waist size, pulse pressure, fasting blood glucose, plasma triglycerides, incidence of coronary artery disease, cerebral hemorrhage and cerebral infarction between groups of different levels of blood pressure (P<0.05, P<0.01). With linear regression analysis, age, BMI, fasting blood glucose and plasma triglycerides were identified as significant and independent risk factors for systolic blood pressure (P<0.05, P<0.01) and only waist size was identified as a significant and independent risk factor for diastolic blood pressure (P<0.01). CONCLUSION: Risk factors for cardiovascular and cerebrovascular diseases increase with the level of blood pressure in subjects with normal blood pressure.