Abstract: AIM To explore the role of coronary artery bypass grafting in septuagenarians. METHODSPreoperative, operative and postoperative data of 94 patients aged≥70 years and data of 10-year follow-up were statistically analyzed, which compared with that of 192 cases aged<70 years. RESULTSThe mean distal anastomoses was not significant between groups. Intubation time, postoperative stay, morbidity of renal function failure and pulmonary infection were longer in the group≥70 years of age than in the<70 year-old group. EF value in the group≥70 years of age was higher than in the group<70 years of age. Ten-year mortality follow-up was significantly higher in the group≥70 years of age than in the group<70 years of age. CONCLUSIONSeptuagenarians had higher morbidities of chronic obstruction pulmonary disease and renal function disease in preoperation, and had more complications and longer postoperative recovery time. Coronary artery bypass grafting (CABG) in patients≥70 years of age can be performed with low mortality and significant symptomatic benefit. Patients should not be denied CABG because of age alone. Survival quality of life in patients≥70 years of age was poorer than in the group<70 years of age.