Abstract: AIM:To study the factors influencing the shortterm prognosis in patients with acute myocardial infarction (AMI) and to assess its predictive value with coronary angiographic findings. METHODS: A retrospective analysis of 108 AMI patients in the critical care unit (CCU) from January 2010 to January 2012 in our hospital was conducted for glucose, lipids, renal function, fibrinogen, creatine kinase, Btype natriuretic peptide and coronary angiographic findings. RESULTS: Average level of serum triglycerides, fasting glucose, average serum urea nitrogen level and average serum uric acid level in event group were higher than those in nonevent group. The mean BNP levels of each time point in event group were all higher than those in nonevent group. The percentage of patients with multivessel lesions in event group was higher than in nonevent group. CONCLUSION: The risk of adverse cardiac events in AMI patients increases with increasing triglycerides. Fasting glucose on admission is one of the high risk factors for cardiac events. Elevated level of serum uric acid and urea nitrogen are shortterm adverse prognostic risk factors for AMI. BNP is a risk for death and cardiovascular events in patients with AMI. Multivessel lesions suggest a high incidence of cardiac events and patients with infarctionrelated artery in LAD have a poorer prognosis than patients with infarctionrelated artery in RCA or LCX.