Abstract:
N6-methyladenosine (m
6A) RNA methylation is the most common, dynamic and reversible epigenetic RNA modification and is involved in the pathogenesis of many human diseases, including cardiovascular diseases. Recent studies have shown that m
6A RNA methylation plays an important regulatory role in myocardial ischemia-reperfusion and cardiac regeneration. Importantly, these new findings suggest that controlling m
6A levels by altering the regulatory factors of m
6A may be a novel and powerful strategy to prevent the deterioration of cardiac functions and promote cardiac repair.