Abstract:
AIM To develop a pre-angiographic prediction model of the need for revascularization in patients after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) over 5 years.
METHODS A retrospective study was conducted in 296 consecutive patients who had undergone PCI for ACS over 5 years. Independent risk factors of the need for revascularization were identified by multivariate analysis and points were assigned according to the corresponding regression coefficients.
RESULTS Multivariate analysis showed that chest pain, troponin I>0.03ng/ml, age at first PCI≤60 years old, initial diameter stenosis at first PCI ≥90% and prior multi-vessel disease were independent risk factors requiring revascularization in patients after PCI for ACS over 5 years. Scores were assigned were respectively 5 points for chest pain, 1 point for troponin I>0.03ng/ml, 1 point for the age at first PCI≤60 years, 2 points for initial diameter stenosis at first PCI ≥90% and 1 point for prior multi-vessel disease. The risk score was used as the test variable and the repeat revascularization was used as the state variable to draw the receiving operating characteristic (ROC) curve, and the area under the curve (AUC) value was 0.822.
CONCLUSION This study presents a risk score that can be used to make a personalized pre-angiographic prediction of the need for revascularization in patients after PCI for ACS over 5 years.