宋兴隆, 吴德喜, 李伟杰, 闫浩东, 张亮, 孙冬冬, 郭文怡. 急性冠脉综合征患者首次经皮冠状动脉介入术后长期生存质量调查及影响因素分析[J]. 心脏杂志, 2022, 34(3): 304-309, 315. DOI: 10.12125/j.chj.202110033
    引用本文: 宋兴隆, 吴德喜, 李伟杰, 闫浩东, 张亮, 孙冬冬, 郭文怡. 急性冠脉综合征患者首次经皮冠状动脉介入术后长期生存质量调查及影响因素分析[J]. 心脏杂志, 2022, 34(3): 304-309, 315. DOI: 10.12125/j.chj.202110033
    Xing-long SONG, De-xi WU, Wei-jie LI, Hao-dong YAN, Liang ZHANG, Dong-dong SUN, Wen-yi GUO. Long-term quality of life in acute coronary syndrome patients after first percutaneous coronary intervention and its influencing factors[J]. Chinese Heart Journal, 2022, 34(3): 304-309, 315. DOI: 10.12125/j.chj.202110033
    Citation: Xing-long SONG, De-xi WU, Wei-jie LI, Hao-dong YAN, Liang ZHANG, Dong-dong SUN, Wen-yi GUO. Long-term quality of life in acute coronary syndrome patients after first percutaneous coronary intervention and its influencing factors[J]. Chinese Heart Journal, 2022, 34(3): 304-309, 315. DOI: 10.12125/j.chj.202110033

    急性冠脉综合征患者首次经皮冠状动脉介入术后长期生存质量调查及影响因素分析

    Long-term quality of life in acute coronary syndrome patients after first percutaneous coronary intervention and its influencing factors

    • 摘要:
        目的  旨在识别急性冠脉综合征(ACS)患者首次经皮冠状动脉介入(PCI)术后长期(>1年)生存质量的影响因素。
        方法  连续纳入451例首次PCI术后1年以上的ACS患者,填写西雅图心绞痛问卷(SAQ),收集基线及复查资料,计算SAQ各维度得分及汇总得分,多因素分析找出其影响因素,通过线性回归建立预测模型。
        结果  首次PCI术后1年以上患者的SAQ身体限制、心绞痛稳定性、心绞痛频率、治疗满意度、疾病认知程度得分分别为70.190±16.972、42.180±19.109、82.680±21.790、88.561±10.448、70.972±23.670, 汇总得分为74.615±15.551。线性回归表明,影响三个以上维度得分的因素为:目前冠心病类型、男性、心绞痛症状发作、首次白细胞计数、首次糖化血红蛋白。
        结论  目前冠心病类型、男性、心绞痛症状发作、首次白细胞计数、首次糖化血红蛋白为ACS患者首次PCI术后长期生存质量的主要影响因素,这些发现有助于临床医生前瞻性地了解哪些患者最有可能从PCI术后长期获益,以尽可能的改善患者的远期生存质量。

       

      Abstract:
        AIM   To identify factors influencing the long-term (>1 year) quality of life (QoL) after first percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS).
        METHODS  A sample of 451 consecutive ACS patients over 1 year after their first PCI was included. The Seattle angina questionnaire (SAQ) was completed and the baseline and review data were collected. The scores of each dimension and summary score of SAQ were calculated, the influencing factors were sorted out by multivariate analysis and the prediction model was established by linear regression.
        RESULTS  More than 1 year after the first PCI, the scores of SAQ physical limitation, angina stability, angina frequency, treatment satisfaction and disease perception were 70.190 ± 16.972, 42.180 ± 19.109, 82.680 ± 21.790, 88.561 ± 10.448 and 70.972 ± 23.670 respectively, and the summary score was 74.615 ± 15.551. Linear regression showed that the factors affecting scores on more than three dimensions were: current type of coronary artery disease, male, angina symptom onset, baseline leukocyte count, and baseline glycosylated hemoglobin.
        CONCLUSION  Current type of coronary heart disease, male, angina symptom onset, baseline leukocyte count, and baseline glycosylated hemoglobin are the main influencing factors of long-term QoL after the first PCI in ACS patients. These findings may help clinicians to prospectively understand which patients are most likely to benefit from the long term after first PCI, so as to improve the long-term QoL of patients as much as possible.

       

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