陈涛, 杨剑, 刘洋, 金屏, 马燕燕, 金振晓, 翟蒙恩. 体外循环在经导管主动脉瓣置换术中的应用[J]. 心脏杂志, 2022, 34(3): 320-324. DOI: 10.12125/j.chj.202107084
    引用本文: 陈涛, 杨剑, 刘洋, 金屏, 马燕燕, 金振晓, 翟蒙恩. 体外循环在经导管主动脉瓣置换术中的应用[J]. 心脏杂志, 2022, 34(3): 320-324. DOI: 10.12125/j.chj.202107084
    Tao CHEN, Jian YANG, Yang LIU, Ping JIN, Yan-yan MA, Zhen-xiao JIN, Meng-en ZHAI. Clinical application of extracorporeal circulation in transcatheter aortic valve replacement[J]. Chinese Heart Journal, 2022, 34(3): 320-324. DOI: 10.12125/j.chj.202107084
    Citation: Tao CHEN, Jian YANG, Yang LIU, Ping JIN, Yan-yan MA, Zhen-xiao JIN, Meng-en ZHAI. Clinical application of extracorporeal circulation in transcatheter aortic valve replacement[J]. Chinese Heart Journal, 2022, 34(3): 320-324. DOI: 10.12125/j.chj.202107084

    体外循环在经导管主动脉瓣置换术中的应用

    Clinical application of extracorporeal circulation in transcatheter aortic valve replacement

    • 摘要:
        目的  探究体外循环技术在经导管主动脉瓣置换(TAVR)术中的应用情况。
        方法  回顾性分析西京医院心血管外科2018年5月~2019年12月期间完成的25例体外循环辅助下TAVR术,分析体外膜肺氧合(ECMO)(n=8)和心肺转流(CPB)(n=15)辅助的临床效果,另有CPB后转为ECMO辅助1例,ECMO后转为CPB又转回ECMO辅助1例。根据临床情况分应急组(n=13)和非应急组(n=12),对患者情况进行对比。
        结果  与ECMO组比较,CPB男性比例低,体质量轻,EF数值高(均P<0.05)。与非应急组比较,应急组男性比例低,体质量轻,EF数值高(均P<0.05)。术中资料与ECMO组比较,CPB组手术时长明显增加(P<0.01);与非应急组比较,应急组手术时长明显增加(P<0.01)。与ECMO组相比, CPB组术后血气动脉氧分压明显增高(P<0.01)、尿量明显减少(P<0.01)、CCU时间明显减少(P<0.01);与非应急组相比, 应急组术后血气动脉氧分压明显增加(P<0.01)、尿量明显增加(P<0.01)、CCU时间明显增加(P<0.01)。
        结论  体外循环是保证TAVR安全开展的必备条件之一。CPB应作为循环辅助的首选方式,ECMO次之。应针对病人的具体情况以及术中出现的各种紧急事件,灵活选择循环辅助方式,以期达到最优效果。

       

      Abstract:
        AIM  To explore the application of extracorporeal circulation in transcatheter aortic valve replacement (TAVR).
        METHODS  We retrospectively analyzed 25 consecutive cases of TAVR assisted by extracorporeal circulation completed from May 2018 to December 2019 in the Department of Cardiovascular Surgery of Xijing Hospital, and compared the efficacy of extracorporeal membrane oxygenation (ECMO, n=8) and cardiopulmonary bypass (CPB, n=15), the left two patients received CPB and ECMO one after another. Besides, we compared the basic conditions of patients in emergency (n=13) and non-emergency (n=12) groups based on clinical experience.
        RESULTS  Compared with the ECMO group, the ratio of male and body weight were lower and the ejection fraction was higher in the CPB group (all P<0.05). Compared with the non-emergency group, the ratio of male and body weight were lower and the ejection fraction was higher in the emergency group (all P<0.05). Compared with the ECMO group, the operation time was significantly increased in the CPB group (P<0.01). Compared with the non-emergency group, the operation time was significantly increased in the emergency group (P<0.01). Compared with the ECMO group, postoperative arterial blood PaO2 (P<0.01) was increased, postoperative urine volume (P<0.01) and CCU time (P<0.01) were significantly decreased in the CPB group. Compared with the non-emergency group, postoperative arterial blood PaO2 (P<0.01), postoperative urine volume (P<0.01) and CCU time (P<0.01) were significantly increased in the non-emergency group.
        CONCLUSION  Extracorporeal circulation is necessary in the process of TAVR. CPB should be the first choice for circulatory assistance, followed by ECMO. But, the circulatory assistance method should be flexibly selected based on the specific conditions of the patient and various emergencies during the operation so as to achieve the best results.

       

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